Causes of Post-Thrombotic Syndrome (PTS)

Angie M
Those that have suffered from deep vein thrombosis, also known as DVT, may find that there can be long term side effects, even after successful treatment. Referred to as PTS or post-thrombotic syndrome, this disorder is considered one of the most common side effects of DVT. Unlike the initial DVT, medication therapy is not successful in treatment of this chronic condition. It is not uncommon for symptoms to improve or go away, only to resurface at a later time.

What Causes Post-Thrombotic Syndrome?

As previously mentioned, PTS is simply a side effect of deep vein thrombosis, affecting approximately 20 to 40% of patients that have suffered from DVT. While the clot is present, irreversible damage is often done to the valves in the extremity, allowing backflow, and this increases venous pressure in the leg. The duration the patient has the clot and the size can all play a role in whether or not this side effect presents itself, however, the damage is not necessarily dependent on these sole factors. Other risks factors include being obese, having multiple DVT's and being of an older age.

Signs and Symptoms

Discoloration of the leg, feet and toes is common among some patients. In addition to this, swelling, pain, tingling and ulcers of the foot may also occur. The signs and symptoms associated with PTS can affect the patient both mentally and physically. The alteration of appearance can be debilitating for some clients. Physically, the swelling and pain can lead to immobility in some. This is because the swelling often increases with long periods of standing or walking, as does numbness, tingling and pain. However, not all patients will exhibit the exact same signs and symptoms. In most cases, the signs and symptoms of post-thrombotic syndrome will appear within six months following the DVT, but can surface up to two years later.

Treatment Options

The treatment for PTS is non-pharmacological. While the patient may continue to take anticoagulants to prevent another blood clot, this does not reduce the side effects of DVT. The most common method for dealing with post-thrombotic syndrome involves the use of compression hose or stockings. These garments are worn on the legs and help regulate the venous pressure of the valves, decreasing the symptoms associated with the syndrome. In certain cases, surgery may be an option for those who have chronically obstructed veins.

Bibliography

Post-Thrombotic Syndrome. Venous Disease Coalition. Modified 19, July 2010. Viewed 12, November 2010. http://www.venousdiseasecoalition.org/diseaseinfo/pts/

DVT: Treatment. Vascular Disease Foundation. Modified 15, October 2010. Viewed 12, November 2010. http://www.vdf.org/diseaseinfo/dvt/treatments.php

Published by Angie M

In addition to freelance writing, I am currently a nursing student. Although many of my articles focus on healthcare and related topics, I write about a variety of things. Specialties include marketing,ghost...  View profile

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