Cystic Fibrosis & the Mystery of Clubbing of the Fingertips and Toes

Kathi Downs
Clubbing of the fingertips may be caused by chronically low blood-oxygen levels, as seen in those with cystic fibrosis.

The appearance of the fingertips changes drastically once clubbing begins. To begin with, there is a softening of the nail bed. Then the area around the cuticle enlarges, and the angle between the cuticle and nail changes. After the cuticle area enlarges, the nail itself becomes convex, much like the curved part of an upside down spoon. The entire end of the fingertips become thicker. Striations then start showing up in the nail, and the entire area around the nail becomes shiny.

Cystic fibrosis is not the only disease that causes clubbing of the fingertips. Clubbing also occurs in people with congenital heart disease. Though clubbing is basically a result of chronic pulmonary or cardiopulmonary disorders, it is also a sign of cancer, usually in some part of the lungs. Though not very common, clubbing has also been associated with certain types of cirrhosis and hyperthyroidism.

Even though clubbing is seen in people with pulmonary disorders, such as cystic fibrosis, it is not associated with COPD - which is Chronic Obstructive Pulmonary Disease. Usually, if a patient that has COPD goes to the doctor because of clubbing, the doctor will start a search for an underlying lung cancer.

As of right now, there is no cure for clubbing. In fact, doctors aren't even quite sure what causes it. The only thing they know for sure is that it usually shows up in people that have lung (pulmonary), heart (cardiac) or heart-lung (cardiopulmonary) disorders, and patients with some types of cancer.

There has not even been research yet as to what causes clubbing, and until they start to research the causes of clubbing, doctors aren't going to know how to treat it.

Published by Kathi Downs

I am the wife and mother of three grown sons; and I have 6 precious grandchildren, 3 boys and 3 girls. Reading and writing has always been a passion of mine.  View profile

  • Clubbing of the fingertips is not only seen in those with Cystic Fibrosis.
  • It affects those with congenital heart problems.
Even though clubbing is seen in people with pulmonary disorders, such as Cystic Fibrosis; it is not associated with COPD.

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