Doxepin Side Effects
The most commonly reported side effects experienced with doxepin are drowsiness, dry mouth and constipation.
Other less severe side effects include: nausea, indigestion, vomiting, diarrhea, raised/decreased libido, weight gain, dizziness, sweating, chills, fatigue, headache, difficulty urinating and temporary blurred vision.
Serious side effects are not generally as common as the less severe side effects. However, due to the nature of these symptoms and their negative effect on a person's health, they should be watched for.
Contact your health care provider if you notice these symptoms: numbness, disorientation, hallucinations, seizures, tardive dyskinesia (involuntary/uncontrollable muscle spasms which may become permanent), raising or lowering of blood sugar levels (in healthy individuals this may not be much of a concern, but for diabetics it could present problems), hyperpyrexia (abnormally high fever, 106.7 degrees Fahrenheit or higher), thrombocytopenia (low levels of blood platelets that are needed to form blood clots) and ataxia (lack of coordination in voluntary muscle movements, such as walking, grasping objects, etc.).
Some people shouldn't take doxepin. People who take monoamine oxidase inhibitors (MAOIs) should not take doxepin while on MAOIs; they should also wait at least two weeks after stopping MAOI treatment before starting doxepin.
Kids and young adults may experience an increased risk of suicidal thoughts and behaviors while on doxepin (and while using other antidepressants as well). Though doxepine is sometimes prescribed to children, the Pfizer package insert states that it has not been approved for use in pediatric patients. They later state that prescribers and caregivers need to weigh the potential benefits versus the risks when prescribing to children.
Doxepin should not be taken with these drugs: MAOIs, alcohol and cimetidine. Caution and close monitoring should be used when combining doxepin with any drug that inhibits cytochrome P450 2D6, including: cimetidine, SSRI antidepressants, quinidine, phenothiazines, propafenone and flecainide.
Sinequan Package Insert,http://media.pfizer.com/files/products/uspi_sinequan.pdf
Published by Laura Munion
I am a freelance writer in Ohio. I specialize in writing about health and fitness topics. My areas of expertise are dental health, autism, and fitness. I have a Bachelor of Science in Electronics Engineering... View profile
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