In fact, sexual behavior is an important factor leading the relapse. The more sexual partners are, the higher the recurrence rate is. The morbidity and recurrence rate of male commercial sex workers are higher than prostitutes' and homosexuals'. The morbidity and recurrence rate of people, whose age having the first sexual behavior were younger than 19, are higher than others'. The risk factors of those women to suffer from Anogenital warts, whose ages having the first sexual behavior were less than 25-year-old, are increased.
Smoking and drinking are risk factors of the morbidity and recurrence of various sexually transmitted diseases, because smoking and drinking can reduce the body's immune function, and people who often smoke and drink have more sexual partners than those who do not smoke and drink. Some survey found that the opportunity for the relapse of genital warts of those people, who smoke more than a decade, increased marked. Moreover, alcohol can inhibit the central nervous system, reduce anxiety, and enhance libido and even prostitution that can result in an increase in sexual partners. At the same time, the increase in violent sexual behavior and the decrease in the use of condoms after drinking increased the extents and opportunities of genital damage, therefore, the morbidity and recurrence of genital warts increased.
Marital status also related to the morbidity and recurrence of the disease, for example, divorcee, the separated couple, widowed and unmarried persons, couples whose married life are disharmony and so on, all those above people, due to increasing in high-risk sexual behavior, will increase the chances of the morbidity and recurrence of genital warts.
Other sexually transmitted diseases, such as genital herpes, gonorrhea, trichomoniasis, syphilis, HIV, fungal infections and so on, could reduce the ability to resist HPV infection through destroying mucosal barrier; otherwise, those diseases could make the local environment around the genitals humid, as is conducive to the propagation and growth of HPV. Various sexually transmitted diseases and other viral or fungal infections significantly reduce the body's resistance to diseases, so the morbidity and recurrence's risk of genital warts have doubled and redoubled.
The morbidity and recurrence risk of genital warts will increase in the immunocompromised hosts, such as cancer patients, patients with SLE (System lupus erythematosus), patients with renal transplants, chemotherapy and so on, besides, they have much bigger warts.
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