Studying Planaria Regeneration to Develop Pharmaceutical Products

Regeneration Occurs Infrequently in Humans, but Plentifully in Planaria

Vincent  Summers
A young man gets his arm caught in a piece of machinery and it is tragically torn off and cannot be rejoined; a military man is near a mine when it explodes and his leg is filled with shrapnel, requiring amputation; a woman, cooking on the stove, accidentally hits the handle of a pot full of boiling liquid, inflicting second and third degree burns on one side of her body. What have all these tragedies got to do with the little flat worms (Platyhelminthes) we call Planaria?

Turning to a Worm for Answers

If only the arm, the leg, or the skin could be re-grown or regenerated! Burned skin would not need grafting, an arm or a leg could grow back. Certainly these things are not happening today, but it could be that much light could be shed on the subject of regeneration by a small pond-dwelling creature. To merely discuss planaria would be to bore the reader, so it consideration is highly recommended of this 55-second video to gain appreciation of its beauty, and its power to fascinate scientists.

Exceptional Regenerative Power of Planaria

Just how extensive is the regenerative power of planaria? It is enormous. Cuts inflicted in the head (without severing) do not automatically kill these worms, but can result in multi-headed creatures. For instance, this eight-headed planarium was produced in just such a fashion. Imagine such regenerative power granted to human beings.

Howard Hughes Medical Institute Video

To obtain a greater appreciation of the diversity of Planaria's regenerative power, consider this video by the Howard Hughes Medical Institute.1 Part two of the video presentation is found here.

Clearly the field of molecular biology is producing some fascinating discoveries that directly affect human welfare. What new discoveries yet remain on the scientific horizon?

1Citation of this video is not meant to imply the author agrees with all of its content. Also, the author does not support the use of stem-cells obtained through abortion of developing humans."

References and Resources:

Gina Mikel - Illustration - Planarium Illustration

Exploratorium - Microscope Imaging Station

Harvard University Life Services Outreach Program - Planaria Regeneration Lab

Science Buddies.org - "Animal Magnetism: Do Magnets Affect Regeneration in Planaria?"

Published by Vincent Summers

My secular expertise includes 23 years of experience at the National Radio Astronomy Observatory, with a share in NASA's extended Voyager 2 effort. I formerly wrote for Demand Studios, Bukisa, Suite 101, Exa...  View profile

20 Comments

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  • Debbie Gavazzi8/4/2010

    Interesting. Thanks for sharing.

  • Teila Tankersley7/25/2010

    Complex and very interesting

  • Catherine Dagger7/25/2010

    Self-healing skin and regenerating limbs and organs sound like sci-fi but who knows?...one day perhaps, hopefully.

  • Vincent Summers7/23/2010

    Yes, I once read the text on Watson & Crick's (with assistance by an X-ray crystallographer named Rosalind Franklin) uncovering of the structure of DNA.

  • Fern Fischer7/22/2010

    Knowledge progressing at warp speed.

  • Fern Fischer7/22/2010

    We had a four-headed planaria in one of my biology classes...way back when they had just "discovered" that DNA was a double-helix. What was high school biology then is in 5th and 6th grade science books now.

  • Darlene Levenson7/22/2010

    Utterly fascinating! And the planaria really are beautiful (thanks for including the video)! Imagine being able to use this little pond-dwelling creature to regenerate human limbs; how amazing. And this wouldn’t have to involve the human stem-cell controversy. We definitely have to pursue our research with molecular biology; in particular with planaria. And research grants have to be made available. Great article!

  • Sondra C7/22/2010

    If only--right? You would think that if plants could do it, humans would also be able to do it. Good article

  • Ambriel Maji7/22/2010

    Very interesting article that I enjoyed reading! I had a friend who lost their arm in a machinery accident that could not be rejoined.

  • Patricia A. Ziegler7/21/2010

    Fascinating.

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