Week One NFL Picks and Predictions

Breaking down the week one NFL picks and predictions is always tough to open a season. These week one NFL predictions include several games that could go either way, including a Baltimore vs. Pittsburgh opener for the AFC North and the Thursday night game of Green Bay vs. New Orleans.

There are several other divisional games that could be pitfalls for those trying to predict outcomes as well, starting with Seattle vs. San Francisco. Many NFL "analysts" are underestimating the Seahawks, and that could lead to overconfidence in San Francisco winning that opening game. Then that Denver vs. Oakland game on Monday night could be as difficult to predict, because both teams really need the win.

Week One NFL Predictions:

New Orleans vs. Green Bay (Thursday Night)
Winner: Saints by 7

Pittsburgh vs. Baltimore
Winner: Steelers by 10

Cincinnati vs. Cleveland
Winner: Browns by 21

Indianapolis vs. Houston
Winner: Texans by 18

Buffalo vs. Kansas City
Winner: Chiefs by 15

Detroit vs. Tampa Bay
Winner: Lions by 9

Philadelphia vs. St. Louis
Winner: Eagles by 16

Atlanta vs. Chicago
Winner: Falcons by 8

Tennessee vs. Jacksonville
Winner: Titans by 4

New York Giants vs. Washington
Winner: Giants by 12

Seattle vs. San Francisco
Winner: Seattle by 3

Minnesota vs. San Diego
Winner: Chargers by 17

Carolina vs. Arizona
Winner: Arizona by 14

Dallas vs. New York Jets (Sunday Night Game)
Winner: Jets by 8

New England vs. Miami (Monday Night Game 1)
Winner: Patriots by 18

Oakland vs. Denver (Monday Night Game 2)
Winner: Broncos by 10

Reference:
Full_Week_One_Schedule