What is a Leydig Cell Tumor?

Tumors arising in Leydig cells, the cells that release testosterone in the testicles, are called Leydig cell tumors. The cause and risk factors are not known. This is a uncommon condition, found in men between 20 and 60 years of age, and may cause early puberty if it affects children.

Symptoms

There are some that can get these tumors without symptoms. Normal signs can include pain in the back or lower abdomen, heaviness in the scrotum, swelling or lumps in the testicle, excess breast tissue development, enlargement of the testicle, and pain or discomfort in the testicle.

Diagnosis

Some of the tests done for this condition other than a physical exam for lumps include a chest x-ray, CT scan of pelvic region and abdomen, scrotum ultrasound, and blood tests. If the testicle is removed, the tissue will be examined.

Treatment

Leydig cell tumor treatment depends on the stage of the cancerous tumor. Stage 1 is just in the testicle. Stage 2 is in the testicle and abdomen lymph nodes. Stage 3 is in the testicle, abdomen lymph nodes, and beyond. There will be the removal of the testicle and possible the nearby lymph nodes. Chemotherapy is given.

Testicular cancer is very treatable and curable. There are many support groups out there for this condition, including the Lance Armstrong Foundation. Some of the complications that can arise from this condition include spreading to the spine, lungs, retroperitoneal area, or the abdomen. Surgical complications can be infertility, bleeding, and infection. The only prevention is to do testicular self-exams to check for lumps and abnormalities.

Source: A.D.A.M.